Disease: Hyperlipoproteinemia Type IIa
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TRIB1 Q96RU8 tribbles pseudokinase 1 Kinase 0.83 0.617 0.577
TNNT2 P45379 troponin T2, cardiac type Cellular structure 2.0E-03 0.601 0.423
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
SLCO1B1 Q9Y6L6 solute carrier organic anion transporter family member 1B1 Transporter 1.1E-21 0.538 0.731
SLC22A3 O75751 solute carrier family 22 member 3 Transporter 7.8E-10 0.531 0.846
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PLA2G15 Q8NCC3 phospholipase A2 group XV Enzyme 0.38 0.520 0.769
PCSK9 Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 2.7E-17 0.482 0.808
NPC1 O15118 NPC intracellular cholesterol transporter 1 Transporter 6.5E-06 0.518 0.692
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
MYBPC3 Q14896 myosin binding protein C3 8.0E-11 0.593 0.385
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808
LPAL2 Q16609 lipoprotein(a) like 2, pseudogene Enzyme 0.626 0.731
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
IL2RB P14784 interleukin 2 receptor subunit beta Receptor 0.29 0.491 0.846
ICAM1 P05362 intercellular adhesion molecule 1 3.5E-02 0.364 0.962
HMGCR P04035 3-hydroxy-3-methylglutaryl-CoA reductase 1.00 0.529 0.692
GLB1 P16278 galactosidase beta 1 Enzyme 7.9E-10 0.448 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962